Double Power Technology T-708 Operator's Manual

Agilent Technologies 708-DS / 709-DS Dissolution ApparatusOperator’s Manual

10 708-DS / 709-DS Operator’s Manual TablesThis page was intentionally left blank, except for this message.

100 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Agilent 708-DS / 709-DS NotificationsMain Screen - Error ConditionsTolerance limi

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 101 If an error occurs during a test, you must clear the error screen manually. Clear

102 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Dialog Screens (Green / Blue)Table 1 5 Dialog Screens (Green / Blue)Delayed Start

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 103 Staggered Manual DropsThe Staggered Manual Drops screen provides a visual indicat

104 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Warning Screens (Yellow)Table 1 6 Warning Screens (Yellow)Instrument Calibration

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 105 Load Dosage PromptThis first warning displays when Apparatus 2 (paddle) or Appara

106 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Instantaneous Spindle Speed JumpIf the spindle speed varies by more than 2% over

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 107 Out of Paper NotificationThis warning is applicable to systems with a printer ins

108 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Lower Drive Unit NotificationDisplays on systems with manual drive units. It indi

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 109 Error Screens (Red)Table 1 7 Error Screens (Red)Parameter Out of RangeThe Paramet

11Agilent Technologies708-DS / 709-DS Dissolution ApparatusOperator’s Manual 1SafetyElectrical Hazards 11The Agilent 708-DS / 709-DS has been designed

110 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Timepoint Overlap ErrorThe Timepoint Overlap error screen displays when the time

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 111 Bath Heater ErrorThe Bath Error - Heater Disabled screen shows all of the possibl

112 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Spindle Speed ErrorThis Spindle Error screen displays when the spindle speed has

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 113 DVH Communications Error (709-DS)DVH communication is tested at the beginning of

114 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS This page was intentionally left blank, except for this message.

115Agilent Technologies708-DS / 709-DS Dissolution ApparatusOperator’s Manual 5Maintenance and TroubleshootingPreventive Maintenance 116Sample Line /

116 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Preventive MaintenancePreventive maintenance intervals may vary depending on th

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 117 4 Following ESD guidelines, inspect all printed circuit board assemblies (PCBA)

118 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting • Please store paddles and basket shafts properly between uses. Do not simply p

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 119 • Please store baskets properly between uses. Do not simply place these baskets

12 708-DS / 709-DS Operator’s Manual1Safety Application of the wrong supply voltage, connection of the instrument to an incorrectly wired supply outle

120 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting 6 Carefully lower the drive unit of the 708-DS / 709-DS until each sample cannu

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 121 drip into the vessel. The bottom of the cup rests on either the paddle blade or

122 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Vessels and Evaporation Covers1 Carefully wash the dissolution vessels after ea

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 123 Water Bath and Temperature Probes (708-DS)Water Bath Care The water bath suppli

124 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Water Bath Temperature Probe Accuracy TestThe temperature probe can be tested u

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 125 Figure 29 Resistance Value of Temperature Probe

126 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Removing or Adjusting Cannulas / ProbesThe manifold of the apparatus may contai

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 127 Accessing the Top CoverRemoving Top Cover1 Ensure the Lift Drive is in the full

128 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Printer MaintenanceRemoving a Thermal Paper RollFigure 30 Near-empty Paper Roll

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 129 1 Place fingers underneath the light-colored handle and pull forward to pop out

Safety 1708-DS / 709-DS Operator’s Manual 13 WarningWARNINGA ‘Warning’ message appears in the manual when failure to observe instructions or precautio

130 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting 2 Internal side levers hold the roll in place. Since it is empty or nearly empt

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 131 Inserting a Thermal Paper Roll (5095-0307)1 With the paper chamber open, insert

132 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Figure 35 Leading Paper and Closing the Lid3 Keeping the paper centered, close

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 133 Figure 37 Feeding Paper

134 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting Thermal Printer TestIn the second Diagnostics screen, press Print Test Sheet to

Maintenance and Troubleshooting 5708-DS / 709-DS Operator’s Manual 135 Obtaining Warranty and Other ServicesTo place a service order (warranty or othe

136 708-DS / 709-DS Operator’s Manual5 Maintenance and Troubleshooting

708-DS / 709-DS Operator’s Manual 135 IndexAAccessories, 23Accuracy TestWater Bath Temperature Probe, 123CCable Connections, 24Cannulas / ProbesRemovi

136 708-DS / 709-DS Operator’s ManualIndex FFigureAccessing the Printer Handle, 128Accessory Installation, 43Affixing the Fasteners, 37Agilent 708-DS

708-DS / 709-DS Operator’s Manual 137Index PPaper RollInserting, 130Removing, 127Parts, 23Power CordConnections, 30Printer Test, 133RRinse Cups, 120Ru

14 708-DS / 709-DS Operator’s Manual1Safety Information Symbols ISwitches main power on 0Switches main power offIndicates single-phase alternati

138 708-DS / 709-DS Operator’s ManualIndex This page was intentionally left blank, except for this message.

15Agilent Technologies708-DS / 709-DS Dissolution ApparatusOperator’s Manual 2IntroductionConventions Used in this Manual 17Serial Number Format 18

16 708-DS / 709-DS Operator’s Manual2 Introduction Agilent’s 708-DS and 709-DS Dissolution Apparatus are designed for dissolution testing of a variety

Introduction 2708-DS / 709-DS Operator’s Manual 17 Conventions Used in this Manual• Items you are asked to press are in bold. For example, “press H on

18 708-DS / 709-DS Operator’s Manual2 Introduction Serial Number FormatThe serial number contains 10 characters and follows this syntax:CC1234xxxxSynt

19Agilent Technologies708-DS / 709-DS Dissolution ApparatusOperator’s Manual 3Setting Up the 708-DS / 709-DSInitial Setup 20Equipment, Parts, and Acce

708-DS / 709-DS Operator’s ManualNotices© Agilent Technologies, Inc. 2014No part of this manual may be reproduced in any form or by any means (includi

20 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Initial SetupComplete the following sections to initially set up the Agilent 708-

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 21 1 Remove the Agilent 708-DS / 709-DS and all other system components from the pac

22 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Environmental Requirements for Installation• Humidity: max relative humidity 80%

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 23 Equipment, Parts, and Accessories As Shipped Parts and AccessoriesLocate the foll

24 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Tubing / Cable ConnectionsComplete the following sections to connect the necessar

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 25 Instrument Level / Water Bath SetupComplete the following sections to properly le

26 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS 1 Remove the black caps from the five (5) screws located on the front, side, and

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 27 Figure 6 Raising the Stability Feet3 Using the 90º Allen key in the top of the fr

28 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS DVH Power Controller Setup (709-DS)1 Install the DVH Power Controller box in the

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 29 Temperature Probe Installation (708-DS)1 Insert the water bath temperature probe

708-DS / 709-DS Operator’s Manual 3 ContentsFigures 7Tab les 91Safety 11Electrical Hazards 11Warning 13Caution 13Note 13Information Symbols 142 Introd

30 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS EVT Probe Installation (708-DS)1 If applicable, insert the EVT Probe cable into t

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 31 Filling the Water Bath (708-DS)1 If necessary, press and hold Drive on the Main

32 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Level Instrument - Re-verification1 With the water bath filled (if applicable), r

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 33 Agilent 708-DS / 709-DS SetupComplete the following sections to set up the Agilen

34 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Vessel Installation1 Press Drive to move the drive unit to the fully raised pos

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 35 Sample Manifold Installation1 From the Main screen, press Menu > Diagnostics.2

36 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Figure 13 Connecting AutoTemp 6 If the unit is equipped with autosampling, locate

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 37 Figure 14 Affixing the FastenersAccessory Installation1 Locate the appropriate ac

38 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Figure 15 Proper Sample Tubing PositionNOTEEnsure that all sample tubing is behin

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 39 Figure 16 Installing Evaporation Covers on Shafts5 Place a shaft locking collar o

4 708-DS / 709-DS Operator’s Manual ContentsDVH Power Controller Setup (709-DS) 28Temperature Probe Installation (708-DS) 29EVT Probe Installation (70

40 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS 6 Insert a DDM or alignment post into the DDM Alignment Shaft hanging from the un

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 41 Figure 19 Inserting DDM into DDM Alignment Shaft7 Repeat the previous step for al

42 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Figure 20 Attaching DDM to Alignment Post9 Repeat the previous step for all appli

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 43 Figure 21 Accessory InstallationSetting Basket (Apparatus 1) Heights1 Ensure the

44 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS Figure 22 Tightening the Shaft Locking Collar7 Raise the drive unit until suffici

Setting Up the 708-DS / 709-DS 3708-DS / 709-DS Operator’s Manual 45 Figure 23 Inserting Height Spheres 3 Lower the drive unit to its operating positi

46 708-DS / 709-DS Operator’s Manual3 Setting Up the 708-DS / 709-DS This page was intentionally left blank, except for this message.

47Agilent Technologies708-DS / 709-DS Dissolution ApparatusOperator’s Manual 4Operating the 708-DS / 709-DSMain Screen - Options 48Menu Screen - Syste

48 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Main Screen - OptionsThe following sections detail the operations available from t

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 49 Main Screen - Sample TemperaturesWhen you press Sample Temperature, the Sample Tem

Contents708-DS / 709-DS Operator’s Manual 5 Menu Screen - System Menu 67Menu Screen - Method Editor 68Menu Screen - Reports 77Menu Screen - Alarms 80M

50 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Place the Vessel Probe in the appropriate vessel and press the corresponding vesse

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 51 Run - Select Method (Automated)You can enter up to five automated methods through

52 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Method - Start Options Table 1 Method - Start OptionsOption FunctionInstant The me

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 53 From the Start Options screen:• Press Ok to start the test with all operational pa

54 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Run - Manual Operation (708-DS)The Apparatus Type and Volume selection is used to

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 55 The Manual Operation screen allows you to run a manual method. Press the rectangul

56 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS • The bath temperature is maintained at the set temperature. If the bath is not at

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 57 Main Screen - StopWhen the system is running, the Stop button is displayed. When y

58 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS active method. The Pause Method button allows for media change during a dissolutio

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 59 A corresponding message is also printed for documentation. Clearing the Pause Alar

6 708-DS / 709-DS Operator’s Manual ContentsWater Bath Care 122Water Bath Temperature Probe Accuracy Test 123Removing or Adjusting Cannulas / Probes 1

60 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Manual Drive Unit Up / Down The manual lift is controlled by a knob on the right s

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 61 Manual Sampling If your Agilent 708-DS / 709-DS is not equipped with the Auto Samp

62 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS The various ports of the standard evaporation cover of the Agilent 708-DS / 709-DS

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 63 Main Screen - LockIn order to lock the instrument, press . The Lock the instrumen

64 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Main Screen - UnlockThe icon indicates that the instrument is currently locked.

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 65 Main Screen - Remote ControlWhen the unit is being controlled remotely, the words

66 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS When the Timer Alarm duration elapses, an Alarm screen displays to notify the user

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 67 Menu Screen - System MenuPress Menu from the Main screen to access the System Menu

68 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - Method EditorThe Method Editor allows you to create a new method, en

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 69 Method Properties Screen 1Table 2 Method Properties Screen 1Option FunctionName 32

708-DS / 709-DS Operator’s Manual 7 FiguresFigure 1. Unpacking 20Figure 2. Removing the Apparatus 21Figure 3. BATH HEATER Connector 24Figure 4. Levele

70 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS From the Method Properties screen:• Press Clear > Yes to return all method par

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 71 From the Method Properties screen:• Press Cancel to exit the routine without savin

72 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Method Properties Screen 3Table 4 Method Properties Screen 2Option FunctionEnable

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 73 From the Method Properties screen:• Press Cancel to exit without saving the values

74 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Method Properties Screen 4Using this Method Properties screen, you can specify up

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 75 All time points are relative to the start of the test. A time point of 000:10:00 a

76 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Method Cancel DialogThe Are you sure? screen displays when Cancel is pressed from

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 77 Menu Screen - ReportsIf a printer is installed, check Enable Printer to enable all

78 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS • To print the contents of a method, press Print Method. The Select Method screen

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 79 Press Print Instrument Settings to print all of the instrument configuration param

8 708-DS / 709-DS Operator’s Manual FiguresFigure 29. Resistance Value of Temperature Probe 124Figure 30. Near-empty Paper Roll 127Figure 31. Accessin

80 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - AlarmsTwo different alarms are available through the Alarms screen:T

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 81 From the Alarms screen:• Press Ok to enable the Timer Alarm and return to the Menu

82 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - InstrumentMenu Screen - Instrument Settings Screen 1Table 6 Menu Scr

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 83 From the Instrument Settings screen:• Press Finish to return to the Menu screen. A

84 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - Instrument Settings Screen 2Table 7 Menu Screen - Instrument Setting

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 85 From the Instrument Settings screen:• Press Back to return to the previous Instrum

86 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - Instrument Settings Screen 4From the Instrument Settings screen:• Pr

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 87 Menu Screen - CalibrationMenu Screen - Calibration Screen 1The Calibration screen

88 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Each of the gray boxes contains a numeric value. The value is the sampling locatio

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 89 Menu Screen - Calibration Screen 2Calibration and Preventative Maintenance due dat

708-DS / 709-DS Operator’s Manual 9 TablesTable 1. Method - Start Options 52Table 2. Method Properties Screen 1 69Table 3. Method Properties Screen 2

90 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - DiagnosticsMenu Screen - Diagnostics Screen 1Table 1 0 Menu Screen -

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 91 From the Diagnostics screen:• Press Next to proceed to the second Diagnostics scre

92 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Menu Screen - Diagnostics Screen 2From the Diagnostics screen:• Press Back to retu

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 93 Diagnostics - DVH Diagnostics Screen 1When a self test is requested, a green check

94 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Diagnostics - DVH Diagnostics Screen 2The DVH screen displays a button for each ve

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 95 Menu Screen - User AccessYou can use user levels to restrict changes to specific i

96 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS General 708-DS / 709-DS ConventionsAlphanumeric Data EntryThe Data Entry screen ac

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 97 Numeric and Time / Date EntryThis screen is a specialized subset of the alphanumer

98 708-DS / 709-DS Operator’s Manual4 Operating the 708-DS / 709-DS Parameter Limits / RangesTable 1 4 Parameter Limits / RangesParameter Range Resolu

Operating the 708-DS / 709-DS 4708-DS / 709-DS Operator’s Manual 99 Manifold Lead Time000:00:00 to 000:01:001 second “Method Properties Screen 3” on p